Category: News

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Research Group Leader (Medicinal Chemistry), Nottingham, UK

Operating from state-of-the-art research facilities in Loughborough and BioCity, Nottingham, UK, Charnwood Molecular is a leading Contract Research Organisation, providing medicinal chemistry, process research and other synthetic chemistry services to the global pharmaceutical, biotechnology and chemical industries.

As part of an ongoing expansion to meet the rising demand for our services, we are now looking to recruit an exceptional individual to contribute to the leadership and management of our project teams at BioCity.

Reporting directly to the Head of Medicinal Chemistry, you will be a key member of our leadership team; your role will involve the design and implementation of new synthetic routes, supporting the day-to-day activities of your team of research chemists, and liaising directly with our clients and collaborators.

Candidate specification:
A BSc, Masters or PhD degree in synthetic organic or medicinal chemistry along with at least 3 years of relevant experience within a biotech, pharmaceutical or contract chemical research organisation.

Previous experience of leading small teams to support drug discovery projects at the hit-to-lead and lead optimization stages would be an advantage, but is not essential.

At Charnwood Molecular we recognise that a company’s real strengths lie in the people that it employs. Our strategy is to recruit the most talented individuals to bring a wealth of creative talent to our team. This is a permanent role offering an competitive salary, benefits and training package, including company pension scheme and medical insurance.

If you have the drive and ambition to help shape the development of a dynamic research-led company located in the heart of the vibrant City of Nottingham, then we look forward to receiving your application.

Please note that all applicants should be eligible to work in the UK.

Call to action:
To be considered, or for further informal discussions, please submit a detailed CV and covering letter: recruitment@charnwood-molecular.com

Charnwood and Forendo

A two-year-long discovery chemistry collaboration between Charnwood Molecular and Forendo Pharma has seen compounds move from discovery to pre-clinical development.

Charnwood Molecular and Forendo Pharma have been collaborating since September 2015, with Charnwood Molecular synthesising challenging steroidal analogues of a hit compound initially identified at Forendo Pharma. Multi-centred lead optimisation efforts led to the identification of a development candidate, for which Charnwood Molecular’s pre-clinical Process Development group scouted various routes for larger-scale synthesis. Studied processes initially delivered multi-gram quantities within the collaboration, before being used by Forendo Pharma to access multi-kilogram quantities of the compound they are now progressing into development.

Dr Robin Wilkes, Director of Business Development at Charnwood Molecular commented: ‘Charnwood Molecular is being increasingly engaged by small companies looking to quickly progress pre-clinical assets into drug development. The infrastructure and partnerships we have developed over the past few years now allow us to do that. We have thoroughly enjoyed working alongside such an excellent collaborator as Forendo Pharma, who we wish every success in taking their development candidates forward’.

“Charnwood Molecular was consistently solving difficult synthetic routes and achieving good results, bringing new ideas and delivering all expectations” added T. Linnanen, Forendo Pharma, Head of Drug Discovery.

About Forendo Pharma

Forendo Pharma is a drug development company that specialises in diseases associated with tissue specific hormone mechanisms. The company is a world-leading innovator in the endometriosis field, with two active programs. Fispemifene, which was developed as part of the company’s men’s health program, is currently used in clinical practice for the treatment of male urological conditions. For further information about Forendo Pharma please see: www.forendo.com
About Charnwood Molecular

About Charnwood Molecular

Charnwood Molecular is a leading CRO providing Drug Discovery and early, pre-clinical Development services. Founded in 1998, we support the Drug Discovery activities of organisations from virtual start-ups to large Pharmaceutical companies. We offer a flexible service from the synthesis of single compounds to the full management of Medicinal Chemistry projects. For further information about Charnwood Molecular please see: www.charnwood-molecular.com

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We’ve now extended our event schedule into 2018 and we have the following representatives at these upcoming events:

Attending: Professor Steven Allin
Event: Heterocyclic and Synthesis Group January Meeting and AGM, London
Date: 12 January 2018
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Attending: Dr Robin Wilkes
Event: Organofluorine Chemistry: Synthetic Methods and Applications, London
Date: 9 February 2018
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Attending: Dr Robin Wilkes
Event: The BMCS Mastering MedChem IV. 4th RSC-BMCS Symposium on Mastering Medicinal Chemistry, Glasgow
Date: 14 March 2018
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Should you wish to meet us at any of these, please email us at:
info@charnwood-molecular.com

Charnwood Molecular has been a key sponsor of Keele University PhD student, Lucy Tunstall, during her trek across the Sahara Desert in aid of St Lukes Hospice in Winsford, Cheshire.

Charnwood Molecular - Lucy Returns

The trek covered a 50km stretch of difficult Saharan terrain, and the trip to and from the desert itself took nine hours, giving some indication of the remoteness of the trail!

Lucy’s group covered the 50 kilometres over a four day period, and in doing so raised over £25,000 for St Lukes Hospice. The group used social media to maintain a blog throughout the trek.

The expedition involved scaling endless sand dunes, battling scorching temperatures by day and sleeping out under the stars.

Lucy has now returned from the group’s base in Marrakesh and is back working and completing her PhD studies. Lucy’s work on the development of novel anti-malarials at Keele is co-funded by Charnwood Molecular.

Lucy is a keen fund raiser and this is just the latest of a series of challenges that she has undertaken to raise funds for St Lukes Hospice.

“I am most grateful to Charnwood Molecular for sponsoring me” said Lucy. “Without the company’s support, I would not have met my funding target to participate, and I am so pleased that I got to undertake this challenge”, she added.

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We are attending the following events and conferences in the coming months.

Event: ELRIG Drug Discovery 2017
Date: 3-4 October 2017
Venue: Liverpool, UK
Charnwood Molecular Representative: Dr Robin Wilkes
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Event: Catalysis without Precious Metals
Date: 17 October 2017
Venue: SCI, London, UK
Charnwood Molecular Representative: Alexandre Jolibois
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Event: 2nd Fibrosis Meeting
Date: 10 November 2017
Venue:SCI, London
Charnwood Molecular Representative: Professor Steven Allin & Dr Robin Wilkes
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Event: WPC Europe
Date: 15-17 November 2017
Venue: Lisbon, Portugal
Charnwood Molecular Representative:Dr Robin Wilkes
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Event: Recent Trends and Technologies in Medicinal Chemistry towards Medicines of the Future
Date: 8 December 2017
Venue: NHLI, London
Charnwood Molecular Representative: Dr Robin Wilkes
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Event: High Potency ADCs – from discovery to the clinic
Date: 11 December 2017
Venue: Cambridge, UK
Charnwood Molecular Representative: Professor Steven Allin
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If you would like to meet any of our representatives at these events, please email:
info@charnwood-molecular.com

Charnwood Molecular received recognition as a finalist in this year’s East Midlands Chamber Business Awards in the “Small Business of the Year” category on Friday evening.

EMA awards line up altered

Photo Caption: from l to r - Dr Mike McKenzie, Paul Hughes, Dr Robin Wilkes, Professor Steven Allin, Dr David Lathbury & Dr James Hitchin.

Professor Steve Allin, Managing Director of Charnwood Molecular, was delighted with the news:
“As we approach our twentieth anniversary as a company, this nomination is testament to the hard work and commitment of the entire team, past and present, at Charnwood Molecular. In that time, and fuelled by significant expansion of our global client base, we have made significant investments into our infrastructure leading to an expansion in our provision in discovery chemistry and process research services, and this nomination recognises our collective efforts in our drive to achieving excellence in our services.”

The award – which was open to organisations employing up to 75 full-time members of staff – recognises companies that have achieved consistent growth backed by a strong financial performance.

We’re recruiting again for a variety of roles, including: Group Leaders, Medicinal and Synthetic Organic Chemists, and Process Research Chemists.

Operating from state-of-the-art research facilities in Loughborough and BioCity (Nottingham), UK, Charnwood Molecular is a leading Contract Research Organisation providing medicinal chemistry, process research and chemical development, and other synthetic chemistry services to the global pharmaceutical, biotechnology and chemical industries.

As part of an ongoing expansion to meet the rising demand for our services, we are looking to recruit a number of experienced individuals to join our project teams in a variety of roles, including: as Group Leaders, Medicinal and Synthetic Organic Chemists, and Process Research Chemists.

Candidate specification:

Ideally PhD qualified, with experience in the following areas:

• Synthetic Organic Chemistry
• Drug Discovery
• Lead Optimisation
• Process Research / Chemical Development

We would also like to hear from graduate level chemists who have several years experience in the industry.

We can offer a competitive salary and benefits, including a company pension scheme.

At Charnwood Molecular we recognise that a company’s real strengths lie in the people that it employs. Our strategy is therefore to employ the most talented chemists to bring a wealth of creative experience to our team. If you have the drive and ambition to help shape the development of a vibrant and dynamic research-led company, then we look forward to receiving your application.

To be considered for these positions please submit a detailed CV and covering letter to:

recruitment@charnwood-molecular.com

We are recruiting for a Business Development Executive to lead on our European operations.

This exciting BD Executive role requires a committed self-starter who is driven to respond proactively to business opportunities and creatively grow the CML business, specifically in Europe. The role requires excellent communication, problem-solving and influencing skills as well as the ability to work effectively as part of a small but growing team. The role may suit an individual with a technical background, with some customer-facing experience, who is now looking to develop their career with a commercial focus, at a particularly exciting stage of the company’s development.

Key Responsibilities
• Revenue generation for assigned territories (Europe) to agreed levels
• Account management of client accounts
• New business development, to grow and enhance the CML business in assigned territories (Europe)
• Arranging client meetings and attending business events
• Reporting progress through our business development infrastructure

Applicant Requirements
We envisage candidates for this exciting position will have some, if not all, of the following attributes:
• Scientific background, to BSc level or beyond
• Previous experience in a customer-facing/BD role within a chemical, pharmaceutical or life sciences environment, though candidates with a strong desire to now develop this area of your career after laboratory experience would also be considered
• Excellent communication skills
• Willingness to travel as required to develop business opportunities

Salary & Location
We offer a competitive salary and benefits, including a company pension scheme. Dependent on experience, this role may be company or home office based, though frequent attendance at the company’s sites would be expected.

Deadline for Applications: We request applications are submitted by 15th October 2017.

If you are interested in applyng for the role, please send your CV, with a covering letter to
recruitment@charnwood-molecular.com

Header for first e-shot re Cambs

Charnwood Molecular are exhibiting at this year’s 19th RSC/SCI Medicinal Chemistry Symposium, which takes place from the 10th to 13th September 2017 at Churchill College, Cambridge.

Our exhibition space is Stand O in Exhibition Marquee

Register with us now, by clicking this link:

RSC/SCI SYMPOSIUM VISITOR REGISTRATION

for the chance to win a specially selected Charnwood Brewery presentation set when you visit the Charnwood Molecular stand at the show.

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Charnwood Molecular will also be launching additional technical papers during this event to complement those already in its extensive library.

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We are attending the forthcoming conferences in the coming months:

Charnwood Molecular Representatives: Aurelie Chabrun and Magda Foreiter
Event: SCI conference – New Synthetic Methods – Design and Application
Date: 28 September 2017
Venue: SCI, London

Charnwood Molecular Representative: Alexandre Jolibois
Event: SCI conference – Catalysis without Precious Metals
Date: 17 October 2017
Venue: SCI, London

If you would like to meet any of our representatives at these events, please email:
info@charnwood-molecular.com