Medicinal Chemistry and Preclinical PR&D: From Discovery Lead to Development Candidate

Medicinal Chemistry and Preclinical PR&D From Discovery Lead to Development Candidate

• European Biotech company
• Supported by 2 FTEs for 18 months
• Discovery chemistry team generated analogues of initial hit
• Multi-centred LO led to identification of Development candidates
• Preclinical R&D group scouted routes and delivered multi-gram quantities of Development compound
• Technology transfer package provided to facilitate cGMP manufacture of multi-kilogram quantities of Development compound

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