Medicinal Chemistry: Hit Finding

Medicinal Chemistry Hit Finding

• UK Biotech company (Immuno-oncology target)
• Supported with 2 FTEs for 6 months
• Computational chemistry through trusted partner
• Construction of homology model of target
• Virtual screening of commercial vendor library
• Novel hit series established (commercial acquisition)
• SAR expanded through wet chemistry
• >40 highly potent compounds with clear SAR

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